| General Information of MET (ID: META00760) |
| Name |
N-Acetyl-1-methylhistidine
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| Synonyms |
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N-Acetyl-1-methylhistidine
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| Source |
Aromatic heteromonocyclic compounds
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| Structure Type |
Amino acids, peptides, and analogues (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic acids and derivatives
Carboxylic acids and derivatives
Amino acids, peptides, and analogues
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| PubChem CID |
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| HMDB ID |
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| Formula |
C9H13N3O3
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| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=53859791"></iframe>
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3D MOL
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2D MOL
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Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
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| ChEBI ID |
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| ChemSpider ID |
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| Physicochemical Properties |
Molecular Weight |
211.22 |
Topological Polar Surface Area |
84.2 |
| XlogP |
-0.7 |
Complexity |
257 |
| Heavy Atom Count |
15 |
Rotatable Bond Count |
4 |
| Hydrogen Bond Donor Count |
2 |
Hydrogen Bond Acceptor Count |
4 |
| Function |
N-Acetyl-1-methylhistidine belongs to the class of organic compounds known as histidine and derivatives. Histidine and derivatives are compounds containing histidine or a derivative thereof resulting from a reaction of histidine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. N-Acetyl-1-methylhistidine is an acetylated derivative of 1-methylhistidine and a very strong basic compound (based on its pKa). It has been found to be associated with chronic kidney disease: the higher the N-acetyl-1-methylhistidine levels, the lower the estimated glomerular filtration rate. This could make N-acetyl-1-methylhistidine a biomarker for chronic kidney disease.
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Regulatory Network
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Induced Change
