| General Information of MET (ID: META00753) |
| Name |
O-Sulfotyrosine
|
| Synonyms |
Click to Show/Hide Synonyms of This Metabolite
(2S)-2-Amino-3-[4-(sulfooxy)phenyl]propanoate; (2S)-2-Amino-3-[4-(sulfooxy)phenyl]propanoic acid; (2S)-2-Amino-3-[4-(sulphooxy)phenyl]propanoate; (2S)-2-Amino-3-[4-(sulphooxy)phenyl]propanoic acid; (2S)-2-Azanyl-3-(4-sulfooxyphenyl)propanoate; (2S)-2-Azanyl-3-(4-sulfooxyphenyl)propanoic acid; (2S)-2-Azanyl-3-(4-sulphooxyphenyl)propanoate; (2S)-2-Azanyl-3-(4-sulphooxyphenyl)propanoic acid; L-Tyrosine O-sulfate; L-Tyrosine O-sulfuric acid; L-Tyrosine O-sulphate; L-Tyrosine O-sulphuric acid; O-SulfO-L-tyrosine; O-Sulfotyrosine; O-SulphO-L-tyrosine; O-Sulphotyrosine; Sulfotyrosine; Sulphotyrosine; Tyrosine O-sulfate; Tyrosine O-sulfuric acid; Tyrosine O-sulphate; Tyrosine O-sulphuric acid; Tyrosine sulfate; Tyrosine sulfuric acid; Tyrosine sulphate; Tyrosine sulphuric acid', O(4')-SulphO-L-tyrosine, 'O-Decasulfate
|
| Source |
Aromatic homomonocyclic compounds
|
| Structure Type |
Amino acids, peptides, and analogues (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic acids and derivatives
Carboxylic acids and derivatives
Amino acids, peptides, and analogues
|
| PubChem CID |
|
| HMDB ID |
|
| Formula |
C9H11NO6S
|
| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=514186"></iframe>
|
 |
|
3D MOL
|
2D MOL
|
|
Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
|
| ChEBI ID |
|
| ChemSpider ID |
|
| Physicochemical Properties |
Molecular Weight |
261.25 |
Topological Polar Surface Area |
135 |
| XlogP |
-2.1 |
Complexity |
354 |
| Heavy Atom Count |
17 |
Rotatable Bond Count |
5 |
| Hydrogen Bond Donor Count |
3 |
Hydrogen Bond Acceptor Count |
7 |
| Function |
O-Sulfotyrosine belongs to the class of organic compounds known as phenylalanine and derivatives. Phenylalanine and derivatives are compounds containing phenylalanine or a derivative thereof resulting from a reaction of phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. O-Sulfotyrosine has been identified as a potential plasma biomarker of reduced kidney function in early chronic kidney disease (CKD), end stage renal disease (ESRD), and hemodialytic clearance. Human plasma levels of O-sulfotyrosine were reported to be influenced by genetic variants in the gene ARSA which codes for the enzyme arylsulfatase A.
|
|
Regulatory Network
|
|
|
|
|
|
|
|
|
click to show the details of this protein
Induced Change
