Details of Metabolite

General Information of MET (ID: META00748)
Name TG(19:0/19:0/22:0)
Synonyms   Click to Show/Hide Synonyms of This Metabolite
1--2--3-Behenoyl-glycerol; 1-Nonadecanoyl-2-nonadecanoyl-3-behenoyl-glycerol; 1-Nonadecanoyl-2-nonadecanoyl-3-docosanoyl-glycerol; 1-Nonadecyloyl-2-nonadecyloyl-3-behenoyl-glycerol; 1-nonadecyloyl-2-nonadecyloyl-3-behenoyl-glycerol ; TG(19:0/19:0/22:0); TG(60:0); TG(60:0) ; Tag(19:0/19:0/22:0); Tag(19:0/19:0/22:0) ; Tag(60:0); Tag(60:0) ; Tracylglycerol(19:0/19:0/22:0); Tracylglycerol(60:0); Triacylglycerol; Triacylglycerol ; Triacylglycerol(19:0/19:0/22:0); Triacylglycerol(19:0/19:0/22:0) ; Triacylglycerol(60:0); Triacylglycerol(60:0) ; Triglyceride
Source Endogenous
Structure Type   Triradylcglycerols  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Glycerolipids
Triradylcglycerols
PubChem CID
9545302
HMDB ID
HMDB0063356
Formula
C63H122O6
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=9545302"></iframe>
3D MOL is unavailable 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
Physicochemical Properties Molecular Weight 975.6 Topological Polar Surface Area 78.9
XlogP 28.4 Complexity 1030
Heavy Atom Count 69 Rotatable Bond Count 62
Hydrogen Bond Donor Count N.A. Hydrogen Bond Acceptor Count 6
Function
TG(19:0/19:0/22:0) belongs to the family of triradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. Their general formula is [R1]OCC(CO[R2])O[R3]. TG(19:0/19:0/22:0) is made up of one nonadecanoyl(R1), one nonadecanoyl(R2), and one docosanoyl(R3).
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Hydrolases (EC 3)
            Glycerol-3-phosphate phosphatase (PGP) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockdown (shRNA) of PGP
                      Induced Change TG(19:0/19:0/22:0) concentration: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that knockdown of PGP leads to the increase of TG(19:0/19:0/22:0) levels compared with control group.
References
1 A phosphoglycolate phosphatase/AUM-dependent link between triacylglycerol turnover and epidermal growth factor signaling. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jun;1863(6):584-594.

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