Details of Metabolite

General Information of MET (ID: META00744)
Name Octadec-9-enoic Acid
Synonyms   Click to Show/Hide Synonyms of This Metabolite
18:1, N-9; 9 Octadecenoic acid; 9-Octadecenoate; 9-Octadecenoic acid; C18:1, N-9; Delta(9)-Octadecenoic acid; Octadec-9-enoate; Oleate; Oleic acid; cis 9 Octadecenoic acid; cis-9-Octadecenoic acid
Source Endogenous
Structure Type   Fatty acids and conjugates  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Fatty Acyls
Fatty acids and conjugates
PubChem CID
965
HMDB ID
HMDB0062703
Formula
C18H34O2
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
ChEBI ID
36021
Physicochemical Properties Molecular Weight 282.5 Topological Polar Surface Area 37.3
XlogP 6.5 Complexity 234
Heavy Atom Count 20 Rotatable Bond Count 15
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 2
Function
Octadec-9-enoic Acid, also known as 18:1, N-9 or Delta(9)-Octadecenoic acid, is classified as a member of the Long-chain fatty acids. Long-chain fatty acids are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms. Octadec-9-enoic Acid is considered to be practically insoluble (in water) and acidic. Octadec-9-enoic Acid can be synthesized from octadec-9-ene. It is also a parent compound for other transformation products, including but not limited to, 1-octadec-9-enoylglycero-3-phosphate, N-(2-hydroxy-1-methylethyl)-9-octadecenamide, and sterculic acid
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Transferases (EC 2)
            Succinate-hydroxymethylglutarate CoA-transferase (SUGCT) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockout of Sugct
                      Induced Change Octadec-9-enoic Acid concentration: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Diabetes mellitus [ICD-11: 5A14]
                      Details It is reported that knockout of Sugct leads to the increase of octadec-9-enoic Acid levels compared with control group.
References
1 Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. Cell Mol Life Sci. 2020 Sep;77(17):3423-3439.

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