General Information of MET (ID: META00724)
Name 15-Methylpalmitate
Synonyms   Click to Show/Hide Synonyms of This Metabolite
15-Methyl hexadecanoate; 15-Methyl hexadecanoic acid; 15-Methyl palmitate; 15-Methyl palmitic acid; 15-Methylpalmitate; 15-Methylpalmitic acid; C17:0; I-17:0; I-C17:0; I17:0; Iso-C17:0; Iso-margarate; Iso-margaric acid; Isomargarate; Isomargaric acid
Source Aliphatic acyclic compounds
Structure Type   Fatty acids and conjugates  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Fatty Acyls
Fatty acids and conjugates
PubChem CID
164860
HMDB ID
HMDB0061709
Formula
C17H34O2
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
ChEBI ID
70850
Physicochemical Properties Molecular Weight 270.5 Topological Polar Surface Area 37.3
XlogP 6.6 Complexity 199
Heavy Atom Count 19 Rotatable Bond Count 14
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 2
Function
15-Methylpalmitate, also known as 15-methylhexadecanoate, is a fatty acid methyl ester (FAME). It has an exact mass of 269.25 g/mol and the molecular formula is C17H33O2. Methylpalmitate is a biomarker for the consumption of butte
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Hydrolases (EC 3)
            Sulfatase sulf-1 (SULF1) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockdown (shRNA) of SULF1
                      Induced Change 15-Methylpalmitate concentration: increase (FC = 2.07)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Ovarian cancer [ICD-11: 2C73]
                      Details It is reported that knockdown of SULF1 leads to the increase of 15-methylpalmitate levels compared with control group.
References
1 Erratum to: Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer. Cancer Metab. 2014 Nov 4;2:24.

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