Details of Metabolite

General Information of MET (ID: META00716)
Name Sedoheptulose 1-phosphate
Synonyms   Click to Show/Hide Synonyms of This Metabolite
Altro-heptulose 1-phosphate; Altro-heptulose 1-phosphoric acid; Sedoheptulose 1-phosphoric acid
Structure Type   Carbohydrates and carbohydrate conjugates  (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic oxygen compounds
Organooxygen compounds
Carbohydrates and carbohydrate conjugates
PubChem CID
16070031
HMDB ID
HMDB0060509
Formula
C7H15O10P
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
KEGG ID
C06222
ChEBI ID
9082
Physicochemical Properties Molecular Weight 290.16 Topological Polar Surface Area 185
XlogP -5 Complexity 313
Heavy Atom Count 18 Rotatable Bond Count 8
Hydrogen Bond Donor Count 7 Hydrogen Bond Acceptor Count 10
Function
This compound belongs to the family of Monosaccharide Phosphates. These are monosaccharides comprising a phosphated group linked tot he carbohydrate unit.
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Hydrolases (EC 3)
            Leukotriene-C4 hydrolase (GGT1) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockdown (siRNA) of GGT1
                      Induced Change Sedoheptulose 1-phosphate concentration: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Renal cell carcinoma [ICD-11: 2C90]
                      Details It is reported that knockdown of GGT1 leads to the increase of sedoheptulose 1-phosphate levels compared with control group.
References
1 Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma. Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6274-E6282.

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