General Information of MET (ID: META00694)
Name 11-Eicosenoic acid
Synonyms   Click to Show/Hide Synonyms of This Metabolite
(EZ)-11-icosenoic acid; (EZ)-eicosenoic acid; (EZ)-icosenoic acid; 11-Eicosenoate; Icos-11-enoate
Source Endogenous;Food
Structure Type   Fatty acids and conjugates  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Fatty Acyls
Fatty acids and conjugates
PubChem CID
5282769
HMDB ID
HMDB0034296
Formula
C20H38O2
Structure
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3D MOL is unavailable 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
FooDB ID
FDB012639
ChemSpider ID
4445896
Physicochemical Properties Molecular Weight 310.5 Topological Polar Surface Area 37.3
XlogP 7.6 Complexity 258
Heavy Atom Count 22 Rotatable Bond Count 17
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 2
Function
11-Eicosenoic acid is found in peanut. Eicosenoic acid is a monounsaturated omega-9 fatty acid found in a variety of plant oils. (Wikipedia
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Hydrolases (EC 3)
            Sulfatase sulf-1 (SULF1) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockdown (shRNA) of SULF1
                      Induced Change 11-Eicosenoic acid concentration: increase (FC = 5.71 / 6.50)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Ovarian cancer [ICD-11: 2C73]
                      Details It is reported that knockdown of SULF1 leads to the increase of 11-eicosenoic acid levels compared with control group.
References
1 Erratum to: Loss of HSulf-1 promotes altered lipid metabolism in ovarian cancer. Cancer Metab. 2014 Nov 4;2:24.

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