| General Information of MET (ID: META00525) |
| Name |
4-Acetamidobutanoic acid
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| Synonyms |
Click to Show/Hide Synonyms of This Metabolite
4-(Acetylamino)butanoate; 4-(Acetylamino)butanoic acid; 4-Acetamidobutanoate; 4-Acetamidobutanoic acid; 4-Acetamidobutyrate; 4-Acetamidobutyric acid; N-Acetyl-4-aminobutanoate; N-Acetyl-4-aminobutanoic acid; N-Acetyl-4-aminobutyrate; N-Acetyl-4-aminobutyric acid; N-Acetyl-gaba; N-Acetyl-gamma-amino-N-butyric acid; N-Acetyl-gamma-aminobutyrate; N4-Acetylaminobutanoate; N4-Acetylaminobutanoic acid
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| Source |
Endogenous;Yeast Metabolite;Food
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| Structure Type |
Amino acids, peptides, and analogues (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic acids and derivatives
Carboxylic acids and derivatives
Amino acids, peptides, and analogues
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| PubChem CID |
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| HMDB ID |
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| Formula |
C6H11NO3
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| Structure |
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=18189"></iframe>
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3D MOL
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2D MOL
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Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
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| KEGG ID |
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| ChEBI ID |
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| FooDB ID |
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| ChemSpider ID |
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| Physicochemical Properties |
Molecular Weight |
145.16 |
Topological Polar Surface Area |
66.4 |
| XlogP |
-0.6 |
Complexity |
133 |
| Heavy Atom Count |
10 |
Rotatable Bond Count |
4 |
| Hydrogen Bond Donor Count |
2 |
Hydrogen Bond Acceptor Count |
3 |
| Function |
4-Acetamidobutanoic acid, also known as 4-acetamidobutanoate or N-acetyl-4-aminobutyric acid, is a member of the class of compounds known as gamma amino acids and derivatives. These compounds are amino acids having an -NH2 group attached to the gamma carbon atom. 4-Acetamidobutanoic acid is soluble (in water) and a weakly acidic compound (based on its pKa). 4-Acetamidobutanoic acid can be found in a number of food items such as Rubus species (blackberry, raspberry), cassava, pepper (C. frutescens), and napa cabbage, which makes 4-acetamidobutanoic acid a potential biomarker for the consumption of these food products. 4-Acetamidobutanoic acid can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to humans. 4-Acetamidobutanoic acid is a GABA derivative, a product of the urea cycle and the metabolism of amino groups, and the product of NAD-linked aldehyde dehydrogenase (EC 1.2.1.3) (KEGG).
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Regulatory Network
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Induced Change