Details of Metabolite

General Information of MET (ID: META00391)
Name	dCDP
Synonyms	Click to Show/Hide Synonyms of This Metabolite 2'-Deoxycytidine 5'-diphosphate, 2'-Deoxycytidine diphosphate, 'D-1beta-Ribofuranosylcytosine diphosphate; 4-Amino-1-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-delta-erythro-pentofuranosyl]-2(1H)-pyrimidinone; D-1b-Ribofuranosylcytosine diphosphoric acid; Deoxy-CDP', Deoxycytidine 5'-diphosphate; Deoxycytidine diphosphate', 2'-Deoxycytidine 5'-diphosphoric acid, 2'-Deoxycytidine diphosphoric acid, 'D-1b-Ribofuranosylcytosine diphosphate; Deoxycytidine diphosphoric acid', 2'-Deoxy-cytidine 5'-pyrophosphate, 2'-Deoxy-cytidine pyrophosphate, 2'-Deoxycytidine-5'-diphosphate, '4-Amino-1-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-D-erythro-pentofuranosyl]-2(1H)-pyrimidinone; delta-1beta-Ribofuranosylcytosine diphosphate
Source	Endogenous;Escherichia Coli Metabolite;Yeast Metabolite;Food;Microbial
Structure Type	Organic pyrophosphates (Click to Show/Hide the Complete Structure Type Hierarchy) Organic oxygen compounds Organic oxoanionic compounds Organic pyrophosphates
PubChem CID	150855
HMDB ID	HMDB0001245
Formula	C9H15N3O10P2
Structure	<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=150855"></iframe>
Structure	3D MOL		2D MOL
	*Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite*
KEGG ID	C00705
ChEBI ID	28846
FooDB ID	FDB022510
ChemSpider ID	132961
METLIN ID	6105
Physicochemical Properties	Molecular Weight	387.18	Topological Polar Surface Area	201
	XlogP	-4.5	Complexity	660
	Heavy Atom Count	24	Rotatable Bond Count	6
	Hydrogen Bond Donor Count	5	Hydrogen Bond Acceptor Count	10
Function	dCDP is a substrate for Uridine-cytidine kinase 1, Nucleoside diphosphate kinase (mitochondrial), Nucleoside diphosphate kinase homolog 5, Ribonucleoside-diphosphate reductase large subunit, Nucleoside diphosphate kinase A, Nucleoside diphosphate kinase 7, Ribonucleoside-diphosphate reductase M2 chain, Nucleoside diphosphate kinase B, Nucleoside diphosphate kinase 3, Nucleoside diphosphate kinase 6 and UMP-CMP kinase.
Regulatory Network
Regulatory Network

Full List of Protein(s) Regulating This Metabolite
Mitochondrial carrier (MC)
Solute carrier family 25 member 33 (SLC25A33)		Click to Show/Hide the Full List of Regulating Pair(s): 1 Pair(s)
Detailed Information	Protein Info click to show the details of this protein
Regulating Pair	Experim Info click to show the details of experiment for validating this pair		[1]
Introduced Variation	Recombinant protein addition of SLC25A33
Induced Change	dCDP concentration: increase
Summary	Introduced Variation Induced Change
Disease Status	Healthy individual
Details	It is reported that recombinant protein addition of SLC25A33 leads to the increase of dCDP levels compared with control group.
Solute carrier family 25 member 36 (SLC25A36)		Click to Show/Hide the Full List of Regulating Pair(s): 1 Pair(s)
Detailed Information	Protein Info click to show the details of this protein
Regulating Pair	Experim Info click to show the details of experiment for validating this pair		[1]
Introduced Variation	Recombinant protein addition of SLC25A36
Induced Change	dCDP concentration: increase
Summary	Introduced Variation Induced Change
Disease Status	Healthy individual
Details	It is reported that recombinant protein addition of SLC25A36 leads to the increase of dCDP levels compared with control group.

References
1	The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters. J Biol Chem. 2014 Nov 28;289(48):33137-48.

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