Details of Metabolite

General Information of MET (ID: META00357)
Name dCTP
Synonyms   Click to Show/Hide Synonyms of This Metabolite
2'-Deoxycytidine 5'-triphosphate, Deoxycytidine 5'-triphosphate, 'Deoxycytidine triphosphate', 2'-Deoxycytidine 5'-triphosphoric acid, Deoxycytidine 5'-triphosphoric acid, 'Deoxycytidine triphosphoric acid', 2'-Deoxycytidine-5'-triphosphate, 'Deoxy-CTP; Deoxycytidine-triphosphate', 2'-Deoxycytidine 5'-triphosphate, 3H-labeled, 2'-Deoxycytidine 5'-triphosphate, p-(32)p-labeled, 2'-Deoxycytidine 5'-triphosphate, magnesium salt, 2'-Deoxycytidine 5'-triphosphate, p''-(32)p-labeled
Source Endogenous;Escherichia Coli Metabolite;Yeast Metabolite;Food;Microbial
Structure Type   Pyrimidine deoxyribonucleotides  (Click to Show/Hide the Complete Structure Type Hierarchy)
Nucleosides, nucleotides, and analogues
Pyrimidine nucleotides
Pyrimidine deoxyribonucleotides
PubChem CID
65091
HMDB ID
HMDB0000998
Formula
C9H16N3O13P3
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
KEGG ID
C00458
DrugBank ID
DB03258
ChEBI ID
16311
FooDB ID
FDB022359
ChemSpider ID
58601
METLIN ID
5929
Physicochemical Properties Molecular Weight 467.16 Topological Polar Surface Area 248
XlogP -5.6 Complexity 823
Heavy Atom Count 28 Rotatable Bond Count 8
Hydrogen Bond Donor Count 6 Hydrogen Bond Acceptor Count 13
Function
Deoxycytidine triphosphate (dCTP) is a cytidine nucleotide triphosphate that is used whenever DNA is synthesized, such as in the polymerase chain reaction. e.g.:.
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Mitochondrial carrier (MC)
            Solute carrier family 25 member 33 (SLC25A33) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Recombinant protein addition of SLC25A33
                      Induced Change dCTP concentration: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that recombinant protein addition of SLC25A33 leads to the increase of dCTP levels compared with control group.
            Solute carrier family 25 member 36 (SLC25A36) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Recombinant protein addition of SLC25A36
                      Induced Change dCTP concentration: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that recombinant protein addition of SLC25A36 leads to the increase of dCTP levels compared with control group.
References
1 The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters. J Biol Chem. 2014 Nov 28;289(48):33137-48.

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