General Information of Protein (ID: PRT01668)
Name Ribosomal protein lateral stalk P2 (RPLP2)
Synonyms   Click to Show/Hide Synonyms of This Protein
60S acidic ribosomal protein P2; Large ribosomal subunit protein P2; Renal carcinoma antigen NY-REN-44; RPLP2; D11S2243E; RPP2
Gene Name RPLP2 Gene ID
6181
UniProt ID
P05387
Family Ribosomal protein (Ribo)
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGKNIEDVIAQGIG
KLASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEKKEESEESDDDMGFGLFD
Structure
1S4J ; 2JDL ; 2LBF ; 2W1O ; 4BEH ; 4V6X ; 5DDZ ; 5GU4
Function Plays an important role in the elongation step of protein synthesis.
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Organic acids and derivatives
            Glutamine Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Glutamine addition (16 hours)
                      Induced Change RPLP2 protein expression levels: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Inflammatory bowel disease [ICD-11: DD72]
                      Details It is reported that glutamine addition causes the increase of RPLP2 protein expression compared with control group.
References
1 Proteomic analysis of glutamine-treated human intestinal epithelial HCT-8 cells under basal and inflammatory conditions. Proteomics. 2006 Jul;6(13):3926-37.

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