Details of Protein

General Information of Protein (ID: PRT01479)
Name Efflux RND transporter periplasmic adaptor (ACRA)
Synonyms   Click to Show/Hide Synonyms of This Protein
Efflux transporter, RND family, MFP subunit
Gene Name acrA Gene ID
58254827
UniProt ID
D0ZEC5
Family Membrane fusion protein (MFP)
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MKKNRGLTPLAAILLFSGSLLLTGCNDDNGATGQRPAPEVGVVTLKTAPLNVSTELPGRT
SAYRIAEVRPQVSGIILKRNFVEGSTVKAGESLYQIDPATYQAAYDSARGDLAKAEAAAN
IAHLTVKRYTPLLGTKYISQQDYDTAVANARQADATVVAAKAAVESARINLAYTKVTSPI
TGLSGKSSVTEGALVTANQSNALVTVQQLDPIYVDVTQSSNDFLRLKQELANGQIKQENG
KASVELVMENGQPYPLKGTLEFSDLTVDESTGSITIRAVFPNPHNDLLPGMFVRARLEEG
VRPDALLVPQQGVTRNPRGQATVMLVGADNKVEMRTIDAAQAIGDQWLVTGGLKSGDRVI
VSGLQRIRPGVQVKVEEAKLNAAVSDGAASGAQQ
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Organic acids and derivatives
            Alanine Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Alanine addition (24 hours)
                      Induced Change ACRA protein abundance levels: increase (FC = 1.45)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that alanine addition causes the increase of ACRA protein abundance compared with control group.
References
1 Alanine Enhances Aminoglycosides-Induced ROS Production as Revealed by Proteomic Analysis. Front Microbiol. 2018 Jan 30;9:29.

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