Details of Protein
| General Information of Protein (ID: PRT01463) | |||||
|---|---|---|---|---|---|
| Name | cDNA FLJ76394 | ||||
| UniProt ID | |||||
| Family | TP53RK-binding protein (TPRKB) | ||||
| Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein | |||||
| Sequence |
MQLTHQLDLFPECRVTLLLFKDVKNAGDLRRKAMEGTIDGSLINPTVIVDPFQILVAANK
AVHLYKLGKMKTRTLSTEIIFNLSPNNNISEALKKFGISVNDTSILIVYIEEGEKQINQE YLISQVEGHQVSLKNLPEIMNITEVKKIYKLSSQEESIGTLLDAIICRMSTKDVL |
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| Function | Highly similar to Homo sapiens CGI-121 protein (CGI-121), mRNA. | ||||
| Regulatory Network | |||||
| Full List of Metabolite(s) Regulating This Protein | ||||||
|---|---|---|---|---|---|---|
| Organic acids and derivatives | ||||||
| Glutamine | Click to Show/Hide the Full List of Regulating Pair(s): 1 Pair(s) | |||||
| Detailed Information |
Metabo Info
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| Regulating Pair |
Experim Info
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[1] | ||||
| Introduced Variation | Glutamine absence (16 hours) | |||||
| Induced Change | cDNA FLJ76394, highly similar to Homo sapiens CGI-121 protein (FC = 0.69) | |||||
| Summary | Introduced Variation
Induced Change
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| Disease Status | Hepatocellular carcinoma [ICD-11: 2C12] | |||||
| Details | It is reported that glutamine absence causes the decrease of cDNA FLJ76394, highly similar to Homo sapiens CGI-121 protein (CGI-121), mRNA protein abundance compared with control group. | |||||
| References | |||||
|---|---|---|---|---|---|
| 1 | Quantitative proteomics analysis reveals glutamine deprivation activates fatty acid -oxidation pathway in HepG2 cells. Amino Acids. 2016 May;48(5):1297-307. | ||||
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