Details of Protein

General Information of Protein (ID: PRT01382)
Name Anthranilate synthase component 1 (TRPE)
Gene Name trpE Gene ID
.
UniProt ID
D0Z7F7
Family Lyases (EC 4)
EC Number   EC: 4.1.3.27  (Click to Show/Hide the Complete EC Tree)
Lyases
Carbon-carbon lyase
Oxo-acid-lyase
EC: 4.1.3.27
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MHQAKTAVTVLTRSAAYSADPTLLFEQLCAQRPATLLLESADIASKHHLKSLLIIDSALR
ITAREREVTLESLSANGAALLTTLRHALPPDVACTCQAHSCTLTFPAQDNEQDEDSRLHT
PSVFDALRTLLSCQPTPDAEPEAMLLGGLFAYDLVAGFEPLPHLSAGPRCPDLCFYLAET
LLILDHRQGSARLQASLFSAAADEYQRLQRRLDALLTEMQRPFKATPVAPCPPLTVEVDR
DDEAFGAIVRDMQRAILAGDIFQAVPSRRFTLPCPAPLAAYRQLKQSNPSPYMFFMQDQA
FTLFGASPESALKYDADSRQVEIYPIAGTRPRGRRADGSIDRDLDGRLELDMRSDPKELA
EHLMLVDLARNDLARICEPGSRYVAELTNVDRYSVVMHLVSRVVGTLRADLDALHAYRAC
MNMGTLSGAPKVRAMQLIAASERRRRGSYGGAVGYLTARGDLDTCIVIRAAYVEDGVASV
QAGAGVVLDSLPQAEADETRSKARAVLNAIAAAHANPPQPQGAI
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Organic acids and derivatives
            Alanine Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Alanine addition (24 hours)
                      Induced Change TRPE protein abundance levels: increase (FC = 6.12)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that alanine addition causes the increase of TRPE protein abundance compared with control group.
References
1 Alanine Enhances Aminoglycosides-Induced ROS Production as Revealed by Proteomic Analysis. Front Microbiol. 2018 Jan 30;9:29.

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