Details of Protein

General Information of Protein (ID: PRT01368)
Name Alpha-1,4 glucan phosphorylase (ETAE_2682)
Gene Name ETAE_2682 Gene ID
.
UniProt ID
D0ZCH8
Family Transferases (EC 2)
EC Number   EC: 2.4.1.1  (Click to Show/Hide the Complete EC Tree)
Transferase
Glycosyltransferase
Hexosyltransferase
EC: 2.4.1.1
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MSYSAESESSESRMQRQIVCALRHRVGMEPAAAGQRDWFNALALVVRDRLYDAYCQTRQR
HAHQQRKRVYYLSMEFLIGQSLRFNLQNLGLYATAQAALAAEGQALEALFDSEPDAALGN
GGLGRLAACFMDSLATLDVAASGHGIKYEYGLFRQLIINDQQIEKPDEWHSAASPWIIQH
PSQSMIIPIYGRIEHGFDAQGNYNPMWLEWKVLLGVPNDYYVSGGEDKGVNRLRLYHAAA
SDSFDILIFNQGDYLQAVGEKIGSENISKILYPSDEILSGKELRLTQEYFLVACTVRDLL
RDFFAEHQDIRRLPEWAAVHINDTHPALIVVELMRVLVDEYRIGWDEAWSMTCRTCSFTN
HTLMPEALECWSLPLVERLLPRHLQLIYEINHRFLTTVSRRYPDDAAPLLPSLSLIDESG
EKRLRMVNLATLGSHKVNGVSAIHSELVRDMLLPQFSRLTPDKFVNQTNGISHRRWLQLA
NPALAQFFTELIGPAWLDDPHRLAQLSDYCDDAQVVDRVRRIKTDNKLALSNYVYSRYRI
ALDPMTMFDVHAKRFHEYKRQLLNVLHIIYQYQRLQEGVELATPKIYFFSGKAAPRYTLA
KLILQLVNCVARRISQLPRVNGVIRVVFLEDYSVSLAERLIPACDLSEQISMAGTEASGT
SNMKFAMNGALLIGTLDGANIEIRQAVGEQNFYLFGHTTLQIAQKKAQGYRPYEVLSQQP
SLQMALDALVSGELCADRELFRPLYEMLTASDYYMHLADFDGYRHAHQQAQLDFSRHTEW
YRRTLRGMSRMGSFSSDYTIRGYCRDIWNTDV
Function Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Organic acids and derivatives
            Alanine Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Alanine addition (24 hours)
                      Induced Change ETAE_2682 protein abundance levels: decrease (FC = 0.55)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that alanine addition causes the decrease of ETAE_2682 protein abundance compared with control group.
References
1 Alanine Enhances Aminoglycosides-Induced ROS Production as Revealed by Proteomic Analysis. Front Microbiol. 2018 Jan 30;9:29.

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