Details of Protein

General Information of Protein (ID: PRT01076)
Name Phosphoglycerate mutase 1 (PGAM1)
Synonyms   Click to Show/Hide Synonyms of This Protein
PGAM 1; BPG-dependent PGAM 1; MPGM 1; Phosphoglyceromutase 1; YKL152C; YKL607; GPM1; GPM
Gene Name GPM1 Gene ID
853705
UniProt ID
P00950
Family Isomerases (EC 5)
EC Number   EC: 5.4.2.11  (Click to Show/Hide the Complete EC Tree)
Isomerase
Mutase
Phosphomutase
EC: 5.4.2.11
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MPKLVLVRHGQSEWNEKNLFTGWVDVKLSAKGQQEAARAGELLKEKKVYPDVLYTSKLSR
AIQTANIALEKADRLWIPVNRSWRLNERHYGDLQGKDKAETLKKFGEEKFNTYRRSFDVP
PPPIDASSPFSQKGDERYKYVDPNVLPETESLALVIDRLLPYWQDVIAKDLLSGKTVMIA
AHGNSLRGLVKHLEGISDADIAKLNIPTGIPLVFELDENLKPSKPSYYLDPEAAAAGAAA
VANQGKK
Structure
1BQ3 ; 1BQ4 ; 1QHF ; 3PGM ; 4PGM ; 5PGM
Function Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also Catalyzes the reaction of EC 5.4.2.4 (synthase), but with a reduced activity.
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Homogeneous non-metal compounds
            Nitrogen Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Nitrogen limitation (1.50 hours)
                      Induced Change GPM1 protein expression levels: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that nitrogen limitation causes the increase of GPM1 protein expression compared with control group.
References
1 Proteome analysis of yeast response to various nutrient limitations. Mol Syst Biol. 2006;2:2006.0026.

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