Details of Protein

General Information of Protein (ID: PRT00960)
Name Armadillo repeat X-linked 2 (ARMCX2)
Synonyms   Click to Show/Hide Synonyms of This Protein
Armcx2; Kiaa0512
Gene Name Armcx2 Gene ID
67416
UniProt ID
Q6A058
Family Eutherian X-chromosome-specific (Armcx)
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MSRARDAGCVAAGIVIGASAWYCVYKYTRGKDQKKKRLTKPKNRASVGTGSRARAGLRAG
FTIDLGPGFSPPNPVDIEIMNKAQGEASNLATTVAEEVAPAAPSPKVQNGAESKVQELNG
AKTEANLESVVMPSATCTVTPPPKVAGGLTAAEAPEIIGAPKVLEAPSTTEASGAVAAPG
PTVSPMIAQTPGPVVPSPTIVSTGPAAIPWAVAHPGAVQSPGPAVPPMAVQSLVPAAPSW
AVVAPPGAVYIPVAAHFAGPAAASRVTQSPGTVIPPLPPPSSVLPRGVPSVPGRTVQSPG
AAVHPVAAQSTGVVVPPRAVQYSGAAVTSGGAAVPSGGAATPRAAASTQRTASTEVMQVP
RVAAATEATETPRIGTPAMVAEASLPVHSGAAENPGTSGSSKTAATGKKAAPGAHTGAIP
KAGSATGAVPKGGGGKGGNKNRSGGKGKNRKNKVDVDELGMGFRPGDGAAAAAAASANGG
QAFLAEIPESEEGESGWTDTESDSDSEPDVPQRGKGKRTIPMHKRPFPYEIDEILGVRDL
RKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMINKTDPHIKEKA
LMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMTITNDYQHLLVN
SIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLGTQVPSSFSSLYNSYVESEILI
NALTLFEIIFDNLRAEVFNYREFNKGSLFYLCTTSGVCVKKIRALANHHDLLVKVKVIKL
VNKF
Function May regulate the dynamics and distribution of mitochondria in neural cells.
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Organic oxygen compounds
            Glucose Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Glucose (low concentration) addition (17.50 hours)
                      Induced Change ARMCX2 protein abundance levels: increase (FC = 2.62)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Cerebral stroke [ICD-11: 8B11]
                      Details It is reported that low glucose addition causes the increase of ARMCX2 protein abundance compared with control group.
References
1 Quantitative Proteomics Reveals the Beneficial Effects of Low Glucose on Neuronal Cell Survival in an in vitro Ischemic Penumbral Model. Front Cell Neurosci. 2020 Sep 1;14:272.

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