Details of Protein

General Information of Protein (ID: PRT00553)
Name Cytochrome C isoform 1 (CYC1)
Synonyms   Click to Show/Hide Synonyms of This Protein
Iso-1-cytochrome c; Cytochrome c aerobic isoform; YJR048W; J1653; CYC1
Gene Name CYC1 Gene ID
853507
UniProt ID
P00044
Family Cytochrome (Cyt)
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MTEFKAGSAKKGATLFKTRCLQCHTVEKGGPHKVGPNLHGIFGRHSGQAEGYSYTDANIK
KNVLWDENNMSEYLTNPKKYIPGTKMAFGGLKKEKDRNDLITYLKKACE
Structure
1CHH ; 1CHI ; 1CHJ ; 1CIE ; 1CIF ; 1CIG ; 1CIH ; 1CRG ; 1CRH ; 1CRI ; 1CRJ ; 1CSU ; 1CSV ; 1CSW ; 1CSX ; 1CTY ; 1CTZ ; 1FHB ; 1IRV ; 1IRW ; 1KYO ; 1LMS ; 1NMI ; 1RAP ; 1RAQ ; 1S6V ; 1U74 ; 1YCC ; 1YFC ; 1YIC ; 2B0Z ; 2B10 ; 2B11 ; 2B12 ; 2BCN ; 2GB8 ; 2HV4 ; 2JQR ; 2JTI ; 2LIR ; 2LIT ; 2MHM ; 2N18 ; 2ORL ; 2PCC ; 2YCC ; 3CX5 ; 3TYI ; 4MU8 ; 4N0K ; 4P4Q ; 4Q5P ; 4QAO ; 4YE1 ; 5CIB ; 5CIC ; 5CID ; 5CIE ; 5CIF ; 5CIG ; 5CIH ; 5KKE ; 5KLU ; 5KPF ; 5LFT ; 5LYC ; 5NCV ; 5T7H ; 5T8W ; 6EGY ; 6EGZ ; 6GD6 ; 6GD7 ; 6GD8 ; 6GD9 ; 6GDA ; 6P41 ; 6P42 ; 6P43 ; 6RGI ; 6RSI ; 6RSJ ; 6RSK ; 6RSL ; 6S8Y ; 6SUY
Function Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of ubiquinol-cytochrome c oxidoreductase. Cytochrome c then transfers this electron to the dinuclear copper A center (CU(A)) of the COX2 subunit of cytochrome oxidase, the final protein carrier in the mitochondrial electron-transport chain. Isoform 1 (CYC1) is the predominant cytochrome c during aerobic/normoxic growth.
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Organic oxygen compounds
            Glucose Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Glucose addition (1.50 hours)
                      Induced Change CYC1 protein expression levels: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Healthy individual
                      Details It is reported that glucose addition causes the increase of CYC1 protein expression compared with control group.
References
1 Proteome analysis of yeast response to various nutrient limitations. Mol Syst Biol. 2006;2:2006.0026.

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