Details of Protein

General Information of Protein (ID: PRT00467)
Name Stromal cell-derived factor 4 (SDF4)
Synonyms   Click to Show/Hide Synonyms of This Protein
Cab45; 45 kDa calcium-binding protein; SDF-4; Sdf4; Cab45
Gene Name Sdf4 Gene ID
20318
UniProt ID
Q61112
Family Calcium-binding protein (CBP)
  Click to Show/Hide the Molecular/Functional Data (Sequence/Structure/Function) of This Protein
Sequence
MVWLVAMTPRQSSLCGLAAHGLWFLGLVLLMDATARPANHSSTRERAANREENEIMPPDH
LNGVKLEMDGHLNKDFHQEVFLGKDMDGFDEDSEPRRSRRKLMVIFSKVDVNTDRRISAK
EMQHWIMEKTAEHFQEAVKENKLHFRAVDPDGDGHVSWDEYKVKFLASKGHNEREIAEAI
KNHEELKVDEETQEVLGNLRDRWYQADNPPADLLLTEDEFLSFLHPEHSRGMLKFMVKEI
FRDLDQDGDKQLSLPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTME
ELENYMDPMNEYNALNEAKQMIAIADENQNHHLEPEEILKYSEFFTGSKLMDYARNVHEE
F
Function May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
Regulatory Network
Full List of Metabolite(s) Regulating This Protein
      Organic oxygen compounds
            Glucose Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Metabo  Info click to show the details of this metabolite
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Glucose (low concentration) addition (17.50 hours)
                      Induced Change SDF4 protein abundance levels: increase (FC = 3.05)
                      Summary Introduced Variation         Induced Change 
                      Disease Status Cerebral stroke [ICD-11: 8B11]
                      Details It is reported that low glucose addition causes the increase of SDF4 protein abundance compared with control group.
References
1 Quantitative Proteomics Reveals the Beneficial Effects of Low Glucose on Neuronal Cell Survival in an in vitro Ischemic Penumbral Model. Front Cell Neurosci. 2020 Sep 1;14:272.

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