| Regulating Pair |
| Introduced Variation |
Knockout of MFSD2A |
Protein Info
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| Induced Change |
LPC [14C]DHA concentration: increase |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of LPC [14C]DHA concentration after MFSD2A knockout through HPLCMS/MS based metabolomics. |
| Disease Status |
Healthy individual |
| Subcellular Location |
Membrane (Cell membrane); Endoplasmic reticulum (Endoplasmic reticulum membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that knockout of MFSD2A leads to the increase of LPC [14C]DHA levels compared with control group. |
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| References |
| 1 |
Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid. Nature. 2014 May 22;509(7501):503-6.
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