| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of liothyronine concentration after SLC7A5 overexpression through 25I-labeled T4, T3, rT3, 3,3-T2 kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
COS1 cells (Immortalized African monkey kidney cells) |
Kidney |
| Subcellular Location |
Membrane (Cell membrane; Apical cell membrane); Lysosome (Lysosome membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that overexpression of SLC7A5 leads to the increase of liothyronine levels compared with control group in COS1 cells. |
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Induced Change