| Regulating Pair |
| Introduced Variation |
Overexpression of SLC38A5 |
Protein Info
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| Induced Change |
Glutamine concentration: increase (FC = 3.5 - 5.5) |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of L-glutamine concentration after SLC38A5 overexpression through kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
HepG2 cells (Human hepatoma cells) |
Liver |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that overexpression of SLC38A5 leads to the increase of glutamine levels compared with control group in HepG2 cells. |
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| References |
| 1 |
Structure, function, and tissue expression pattern of human SN2, a subtype of the amino acid transport system N. Biochem Biophys Res Commun. 2001 Mar;281(5):1343-8.
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