| Regulating Pair |
| Introduced Variation |
Overexpression of SLC7A5 |
Protein Info
|
| Induced Change |
Histidine concentration: increase |
Metabo Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of L-histidine concentration after SLC7A5 overexpression through 3H-or 14C-labeled amino acids kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
Xenopus laevis oocytes |
N.A. |
| Subcellular Location |
Membrane (Cell membrane; Apical cell membrane); Lysosome (Lysosome membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that overexpression of SLC7A5 leads to the increase of histidine levels compared with control group in xenopus laevis oocytes. |
|
|
|
|
|
|
|
| References |
| 1 |
Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues. Biochemistry. 2001 Oct 16;40(41):12387-94.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
