| Regulating Pair |
| Introduced Variation |
Overexpression of Slc47a1 |
Protein Info
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| Induced Change |
Arginine concentration: increase (FC = 12 - 20) |
Metabo Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of L-arginine concentration after Slc47a1 overexpression through [3H]labeled amino acids kit detection. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
Xenopus laevis oocytes |
N.A. |
| Subcellular Location |
Membrane (Cell membrane) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that overexpression of Slc47a1 leads to the increase of arginine levels compared with control group in xenopus laevis oocytes. |
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| References |
| 1 |
Human cationic amino acid transporters hCAT-1, hCAT-2A, and hCAT-2B: three related carriers with distinct transport properties. Biochemistry. 1997 May 27;36(21):6462-8.
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