| Regulating Pair |
| Introduced Variation |
Overexpression of SLC38A8 |
Protein Info
|
| Induced Change |
Arginine concentration: increase |
Metabo Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the change of L-arginine concentration after SLC38A8 overexpression through Uptake assay and two-microelectrode voltage clamp based metabolomics. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
Xenopus laevis oocytes |
N.A. |
| Subcellular Location |
Membrane |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that overexpression of SLC38A8 leads to the increase of arginine levels compared with control group in xenopus laevis oocytes. |
|
|
|
|
|
|
|
| References |
| 1 |
Transport of L-glutamine, L-alanine, L-arginine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS. J Mol Biol. 2015 Mar 27;427(6 Pt B):1495-1512.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
