| Regulating Pair |
| Introduced Variation |
Arginine addition (8.3310^-4 hours) |
Metabo Info
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| Induced Change |
EIF4EBP1 protein phosphorylation levels: decrease |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of EIF4EBP1 protein phosphorylation abundances after arginine addition through immunoblot analysis. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
Iec-18 cells (Intestinal epithelial cells) |
Ileum |
| Subcellular Location |
Cytoplasm (Cytosol; Postsynaptic Cytoplasm); Nucleus |
| Tested Species |
Species: Rattus norvegicus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Rattus
Species: Rattus norvegicus
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| Details |
It is reported that arginine addition causes the decrease of EIF4EBP1 protein phosphorylation compared with control group in the Iec18 cells. |
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| References |
| 1 |
Glutamine is a key regulator for amino acid-controlled cell growth through the mTOR signaling pathway in rat intestinal epithelial cells. Biochem Biophys Res Commun. 2005 Jan 7;326(1):174-80.
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