Regulating Pair
       Introduced Variation Valine addition (3 hours) Metabo Info
       Induced Change AKT1 protein phosphorylation levels: increase Protein Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the variation of AKT1 protein phosphorylation abundances after valine addition through western blot analysis.
       Disease Status Acute lymphoblastic leukemia ICD-11: 2B33
       Organ/Tissue/Cell Line RAW 264.7 cells (Mouse mononuclear macrophage leukemic cells) Mouse peripheral blood
       Subcellular Location Cytoplasm; Nucleus; Membrane (Cell membrane)
       Tested Species   Species: Mus musculus  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
       Details It is reported that valine addition causes the increase of AKT1 protein phosphorylation compared with control group in the RAW2647 cells.
References
1 Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207.

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