| Regulating Pair |
| Introduced Variation |
5-oxo-ETE addition (24 hours) |
Metabo Info
|
| Induced Change |
AKT2 protein phosphorylation levels: increase |
Protein Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of AKT2 protein phosphorylation abundances after 5-oxo-ETE addition through western blot analysis. |
| Disease Status |
Pulmonary hypertension |
ICD-11: BB01 |
| Organ/Tissue/Cell Line |
CHO/TG1019 cells (Chinese hamster ovary cells expressing TG1019) |
Ovary |
| Subcellular Location |
Cytoplasm; Nucleus; Membrane (Cell membrane); Endosome (Early endosome) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that 5-oxo-ETE addition causes the increase of AKT2 protein phosphorylation compared with control group in the CHO-TG1019 cells. |
|
|
|
|
|
|
|
| References |
| 1 |
TG1019/OXE, a Galpha(i/o)-protein-coupled receptor, mediates 5-oxo-eicosatetraenoic acid-induced chemotaxis. Biochem Biophys Res Commun. 2005 Sep 9;334(4):987-95.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
