Details of Experiment

Regulating Pair
       Introduced Variation Resolvin E1 addition (0.08 hours) Metabo Info
       Induced Change MAPK1 protein phosphorylation levels: increase Protein Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the variation of MAPK1 protein phosphorylation abundances after resolvin E1 addition through immunoblot analysis.
       Disease Status Coronary artery disease ICD-11: BA80
       Organ/Tissue/Cell Line HEK 293 cells (Human embryonic kidney cells) Kidney
Peripheral blood monocytes Peripheral blood
       Subcellular Location Cytoplasm (Cytoskeleton; Spindle); Nucleus; Centrosome; Cytoplasm; Membrane (caveola)
       Tested Species   Species: Homo sapiens  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
       Details It is reported that resolvin E1 addition causes the increase of MAPK1 protein phosphorylation compared with control group in the HEK293 cells and Peripheral blood monocytes.
References
1 Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. J Exp Med. 2005 Mar 7;201(5):713-22.

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