Regulating Pair
       Introduced Variation Leucine addition (5 hours) Metabo Info
       Induced Change MAPK8 protein phosphorylation levels: increase Protein Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the variation of MAPK8 protein phosphorylation abundances after leucine addition through macroarray analysis.
       Disease Status Healthy individual
       Organ/Tissue/Cell Line N.A. Duodenum
       Subcellular Location Cytoplasm; Nucleus; Cell junction (Synapse)
       Tested Species   Species: Homo sapiens  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
       Details It is reported that leucine addition causes the increase of MAPK8 protein phosphorylation compared with control group in the human duodenal biopsy samples.
References
1 Influence of leucine on protein metabolism, phosphokinase expression, and cell proliferation in human duodenum1,3. Am J Clin Nutr. 2011 Jun;93(6):1255-62.

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