| Regulating Pair |
| Introduced Variation |
Glutamine addition (1 hours) |
Metabo Info
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| Induced Change |
RPS6KB1 protein abundance levels: increase |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of RPS6KB1 protein abundances after L-glutamine addition through In-cell western assay analysis or western blot analysis. |
| Disease Status |
Ovarian cancer |
ICD-11: 2C73 |
| Organ/Tissue/Cell Line |
Hela cells (Human cervix carcinoma cells) |
Cervix uteri |
| Subcellular Location |
Cell junction (Synaptosome); Mitochondrion (Mitochondrion outer membrane); Nucleus; Cytoplasm |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that glutamine addition causes the increase of RPS6KB1 protein abundance compared with control group in the Hela cells and IPEC-1. |
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| References |
| 1 |
Bidirectional transport of amino acids regulates mTOR and autophagy. Cell. 2009 Feb 6;136(3):521-34.
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