| Regulating Pair |
| Introduced Variation |
Arginine decrease (20 hours) |
Metabo Info
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| Induced Change |
RPS6KB1 protein abundance levels: decrease |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of RPS6KB1 protein abundances after asparagine decrease through western blot analysis. |
| Disease Status |
Salmonellae infection |
ICD-11: 1A09 |
| Organ/Tissue/Cell Line |
T cells |
Spleen |
| Subcellular Location |
Cytoplasm; Cell junction (Synapse; Synaptosome); Mitochondrion (Mitochondrion outer membrane) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that arginine decrease causes the decrease of RPS6KB1 protein abundance compared with control group in the T cells (C57BL/6J mice). |
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| References |
| 1 |
Asparagine deprivation mediated by Salmonella asparaginase causes suppression of activation-induced T cell metabolic reprogramming. J Leukoc Biol. 2016 Feb;99(2):387-98.
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