| Regulating Pair |
| Introduced Variation |
Methionine decrease (504 hours) |
Metabo Info
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| Induced Change |
COX5B protein expression levels: decrease |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of COX5B protein abundances after methionine decrease through 2-DE or silver staining analysis. |
| Disease Status |
Stomach cancer |
ICD-11: 2B72 |
| Organ/Tissue/Cell Line |
SGC7901 cells (Human gastric carcinoma cells) |
Stomach |
| Subcellular Location |
Mitochondrion (Mitochondrion inner membrane) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that methionine decrease causes the decrease of COX5B protein expression compared with control group in the SGC7901 cells. |
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| References |
| 1 |
Applying proteomic methodologies to analyze the effect of methionine restriction on proliferation of human gastric cancer SGC7901 cells. Clin Chim Acta. 2007 Feb;377(1-2):206-12.
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