| Regulating Pair |
| Introduced Variation |
Arginine decrease (0.25 hours) |
Metabo Info
|
| Induced Change |
MYC protein abundance levels: decrease |
Protein Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of MYC protein abundances after asparagine decrease through western blot analysis. |
| Disease Status |
Salmonellae infection |
ICD-11: 1A09 |
| Organ/Tissue/Cell Line |
T cells |
Spleen |
| Subcellular Location |
Nucleus (Nucleoplasm; Nucleolus) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
|
| Details |
It is reported that arginine decrease causes the decrease of MYC protein abundance compared with control group in the T cells (C57BL/6J mice). |
|
|
|
|
|
|
|
| References |
| 1 |
Asparagine deprivation mediated by Salmonella asparaginase causes suppression of activation-induced T cell metabolic reprogramming. J Leukoc Biol. 2016 Feb;99(2):387-98.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
