| Regulating Pair |
| Introduced Variation |
Lactic acid addition (6 hours) |
Metabo Info
|
| Induced Change |
MYC mRNA levels: increase (FC = 1.3) |
Protein Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of MYC abundances after through quantitative real-time RT-PCR analysis. |
| Disease Status |
Cervical Cancer |
ICD-11: 2C77 |
| Organ/Tissue/Cell Line |
SiHa cells (Cervical cancer cells) |
Cervix uteri |
| Subcellular Location |
Nucleus (Nucleoplasm; Nucleolus) |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that lactic acid addition causes the increase of MYC mRNA levels compared with control group in the SiHa cells and Hela Cells. |
|
|
|
|
|
|
|
| References |
| 1 |
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells. Cell Cycle. 2016;15(1):72-83.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
