Details of Experiment

Regulating Pair
       Introduced Variation Lactic acid addition (6 hours) Metabo Info
       Induced Change MYC protein expression levels: increase (FC = 1.3) Protein Info
       Summary Introduced Variation         Induced Change 
Full List of Experiment(s) Validating This Regulating Pair
Details of Experiment for Validating This Pair [1]
       Method Quantifying the variation of MYC protein abundances after lactate addition through western blot analysis.
       Disease Status Cervical Cancer ICD-11: 2C77
       Organ/Tissue/Cell Line SiHa cells (Cervical cancer cells) Cervix uteri
Hela cells (Human cervix carcinoma cells) Cervix uteri
       Subcellular Location Nucleus (Nucleoplasm; Nucleolus)
       Tested Species   Species: Homo sapiens  (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
       Details It is reported that lactic acid addition causes the increase of MYC protein expression compared with control group in the SiHa cells and Hela Cells.
References
1 Lactate promotes glutamine uptake and metabolism in oxidative cancer cells. Cell Cycle. 2016;15(1):72-83.

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