| Regulating Pair |
| Introduced Variation |
Oxoglutaric acid addition (336 hours) |
Metabo Info
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| Induced Change |
PSMA5 protein expression levels: decrease |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of PSMA5 protein abundances after alpha-ketoglutarate addition through MALDI-TOF/MS analysis. |
| Disease Status |
Parkinsonism |
ICD-11: 8A00 |
| Organ/Tissue/Cell Line |
N.A. |
Pituitary |
| Subcellular Location |
Cytoplasm; Nucleus |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that oxoglutaric acid addition causes the decrease of PSMA5 protein expression compared with control group in the gilthead sea bream pituitary. |
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| References |
| 1 |
Dietary keto-acid feed-back on pituitary activity in gilthead sea bream: effects of oral doses of AKG. A proteomic approach. Gen Comp Endocrinol. 2010 Dec 1;169(3):284-92.
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