| Regulating Pair |
| Introduced Variation |
Glucose addition (50 hours) |
Metabo Info
|
| Induced Change |
MAPK14 protein abundance levels: increase |
Protein Info
|
| Summary |
Introduced Variation
Induced Change
|
|
|
|
|
|
|
|
| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of MAPK14 protein abundances after glucose addition through western blot analysis. |
| Disease Status |
Brain cancer |
ICD-11: 2A00 |
| Organ/Tissue/Cell Line |
U87-EGFRvIII cells (Human glioma cells expressing EGFRvIII) |
Brain |
| U87 cells (Human glioma cells) |
Brain |
| Subcellular Location |
Cytoplasm; Nucleus |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
|
| Details |
It is reported that glucose addition causes the increase of MAPK14 protein abundance compared with control group in the U87-EGFRvIII cells and U87 cells. |
|
|
|
|
|
|
|
| References |
| 1 |
Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Mol Syst Biol. 2012 Jun 26;8:589.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.
