| Regulating Pair |
| Introduced Variation |
Glutamine addition (6 hours) |
Metabo Info
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| Induced Change |
NOS2 protein expression levels: decrease |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of NOS2 protein abundances after glutamine addition through westen blot analysis. |
| Disease Status |
Sepsis |
ICD-11: 1G40 |
| Organ/Tissue/Cell Line |
N.A. |
Lung |
| Subcellular Location |
Cytoplasm (Cytosol) |
| Tested Species |
Species: Rattus norvegicus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Rattus
Species: Rattus norvegicus
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| Details |
It is reported that glutamine addition causes the decrease of NOS2 protein expression compared with control group in the lung tissues. |
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| References |
| 1 |
GLUTAMINE PREVENTS ACTIVATION OF NF-kappaB AND STRESS KINASE PATHWAYS, ATTENUATES INFLAMMATORY CYTOKINE RELEASE, AND PREVENTS ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FOLLOWING SEPSIS. Shock. 2005 Dec;24(6):583-9.
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