| Regulating Pair |
| Introduced Variation |
Arginine decrease (16 hours) |
Metabo Info
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| Induced Change |
NOS2 protein expression levels: decrease |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of NOS2 protein abundances after arginine decrease through immunoprecipitation analysis. |
| Disease Status |
Peritonitis |
ICD-11: DC50 |
| Organ/Tissue/Cell Line |
Mouse inflammatory peritoneal macrophages |
Bone marrow |
| Subcellular Location |
Cytoplasm (Cytosol) |
| Tested Species |
Species: Mus musculus (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Rodentia
Family: Muridae
Genus: Mus
Species: Mus musculus
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| Details |
It is reported that arginine decrease causes the decrease of NOS2 protein expression compared with control group in the mouse inflammatory peritoneal macrophages. |
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| References |
| 1 |
Translational control of inducible nitric oxide synthase by IL-13 and arginine availability in inflammatory macrophages. J Immunol. 2003 Nov 1;171(9):4561-8.
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