| Regulating Pair |
| Introduced Variation |
Glutamine absence (16 hours) |
Metabo Info
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| Induced Change |
RGN protein abundance levels: increase (FC = 7.28) |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of RGN protein abundances after glutamine absence through quantitative LC-MS/MS analysis. |
| Disease Status |
Hepatocellular carcinoma |
ICD-11: 2C12 |
| Organ/Tissue/Cell Line |
HepG2 cells (Human hepatocellular carcinoma cells) |
Liver |
| Subcellular Location |
Cytoplasm |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that glutamine absence causes the increase of RGN protein abundance compared with control group in the HepG2 cells. |
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| References |
| 1 |
Quantitative proteomics analysis reveals glutamine deprivation activates fatty acid -oxidation pathway in HepG2 cells. Amino Acids. 2016 May;48(5):1297-307.
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