| Regulating Pair |
| Introduced Variation |
Glutamine addition (18 hours) |
Metabo Info
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| Induced Change |
IL6 protein expression levels: decrease (FC = 1.2) |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of IL6 protein abundances after glutamine addition through ELISA analysis. |
| Disease Status |
Inflammatory bowel disease |
ICD-11: DD72 |
| Organ/Tissue/Cell Line |
N.A. |
Intestinal epithelium |
| Subcellular Location |
Secreted |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that glutamine addition causes the decrease of IL6 protein expression compared with control group in the human intestinal mucosa. |
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| References |
| 1 |
Modulating effect of glutamine on IL-1beta-induced cytokine production by human gut. Clin Nutr. 2003 Aug;22(4):407-13.
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