| Regulating Pair |
| Introduced Variation |
Glucose decrease (36 hours) |
Metabo Info
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| Induced Change |
FGF4 protein expression levels: decrease |
Protein Info
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| Summary |
Introduced Variation
Induced Change
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| Full List of Experiment(s) Validating This Regulating Pair |
| Details of Experiment for Validating This Pair |
[1] |
| Method |
Quantifying the variation of FGF4 protein abundances after glucose decrease through human angiogenic factor proteome profiler protein array analysis. |
| Disease Status |
Healthy individual |
| Organ/Tissue/Cell Line |
HUCPVC (human umbilical cord perivascular cells) |
Umbilical stalk |
| First Trimester-HUCPVC (First trimester-human umbilical cord perivascular cells) |
Umbilical stalk |
| Subcellular Location |
Secreted |
| Tested Species |
Species: Homo sapiens (Click to Show/Hide the Complete Species Lineage)
Kingdom: Metazoa
Phylum: Chordata
Class: Mammalia
Order: Primates
Family: Hominidae
Genus: Homo
Species: Homo sapiens
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| Details |
It is reported that glucose decrease causes the decrease of FGF4 protein expression compared with control group in the term-human umbilical cord perivascular cells and first trimester-HUCPVC cells. |
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| References |
| 1 |
Glucose withdrawal induces Endothelin 1 release with significant angiogenic effect from first trimester (FTM), but not term human umbilical cord perivascular cells (HUCPVC). Angiogenesis. 2020 May;23(2):131-144.
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