General Information of MET (ID: META01462)
Name	Tauro-alpha/beta/omega-muricholic acid
Structure Type	Lipid-related molecules
Structure
	2D MOL
Regulatory Network

Full List of Protein(s) Regulating This Metabolite
Nuclear hormone receptor (NHR)
PPAR-alpha (PPARA)		Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
Detailed Information	Protein   Info click to show the details of this protein
Regulating Pair	Experim Info click to show the details of experiment for validating this pair					[1]
Introduced Variation	Knockout of Ppara
Induced Change	Tauro-alpha/beta/omega-muricholic acid concentration: increase
Summary	Introduced Variation         Induced Change
Disease Status	Healthy individual
Details	It is reported that knockout of Ppara leads to the increase of tauro-alpha/beta/omega-muricholic acid levels compared with control group.

References
1	Targeted Metabolomics Reveals a Protective Role for Basal PPAR in Cholestasis Induced by -Naphthylisothiocyanate. J Proteome Res. 2018 Apr 6;17(4):1500-1508.

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