Details of Metabolite

General Information of MET (ID: META01455)
Name 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol)
Synonyms   Click to Show/Hide Synonyms of This Metabolite
UNII-T52TI8BMQ6; T52TI8BMQ6; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, sodium salt; 268550-95-4; sodium 1-palmitoyl-2-oleoyl-sn-glycero-3-(phospho-rac-(1-glycerol)); 202070-86-8; POPG Na, l-; POPG Na, r-; POPG-Na, l-
Source Aliphatic acyclic compounds
Structure Type   Glycerophosphoglycerols  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Glycerophospholipids
Glycerophosphoglycerols
PubChem CID
52941750
HMDB ID
HMDB0010574
Formula
C40H76NaO10P
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=52941750"></iframe>
3D MOL is unavailable 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
ChEBI ID
73234
FooDB ID
FDB027724
ChemSpider ID
24768073
Physicochemical Properties Molecular Weight 771 Topological Polar Surface Area 152
XlogP N.A. Complexity 875
Heavy Atom Count 52 Rotatable Bond Count 41
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 10
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Pore-forming PNC peptide (PNC)
            Cellular tumor antigen p53 (TP53) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockout of TP53
                      Induced Change 2-Oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) concentration: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Colon cancer [ICD-11: 2B90]
                      Details It is reported that knockout of TP53 leads to the increase of 2-oleoyl-1-palmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) levels compared with control group.
References
1 Integrative omics analysis of p53-dependent regulation of metabolism. FEBS Lett. 2018 Feb;592(3):380-393.

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