General Information of MET (ID: META01381)
Name	Margaroylcarnitine
Structure Type	Lipid-related molecules
Structure
	2D MOL
Regulatory Network

Full List of Protein(s) Regulating This Metabolite
Oxidoreductases (EC 1)
Formyltetrahydrofolate dehydrogenase (ALDH1L2)		Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
Detailed Information	Protein   Info click to show the details of this protein
Regulating Pair	Experim Info click to show the details of experiment for validating this pair					[1]
Introduced Variation	Mutation of ALDH1L2
Induced Change	Margaroylcarnitine concentration: increase (FC = 0.72)
Summary	Introduced Variation         Induced Change
Disease Status	Genetic disorders of keratinisation [ICD-11: EC20]
Details	It is reported that mutation (patients) of ALDH1L2 leads to the increase of margaroylcarnitine levels compared with control group.

References
1	Deleterious mutations in ALDH1L2 suggest a novel cause for neuro-ichthyotic syndrome. NPJ Genom Med. 2019 Jul 23;4:17.

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