General Information of MET (ID: META01238)
Name 1-Oleoyl-sn-glycerol 3-phosphate
Synonyms   Click to Show/Hide Synonyms of This Metabolite
1-Oleoyl-sn-glycerol 3-phosphate; 1-Oleoyl Lysophosphatidic Acid; 1-Oleoyl-sn-glycero-3-phosphate; lysophosphatidic acid; CHEBI:62837; 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate; PA(18:1/0:0); 65528-98-5; LysoPA(18:1); 1-oleylglycerol 3-phosphate; 1-oleoylglycerol 3-phosphate; Lysophosphatidic acid(18:1); CHEMBL117021; 1-oleyl-sn-glycerol 3-phosphate; LysoPA(18:1w9/0:0); 1-O-oleyl-sn-glycerol 3-phosphate; 18:1 LPA; 1-O-oleoyl-sn-glycerol 3-phosphate
Structure Type   Glycerophosphoethanolamines  (Click to Show/Hide the Complete Structure Type Hierarchy)
Lipids and lipid-like molecules
Glycerophospholipids
Glycerophosphoethanolamines
PubChem CID
5311263
Formula
C21H41O7P
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=5311263"></iframe>
3D MOL is unavailable 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
Physicochemical Properties Molecular Weight 436.5 Topological Polar Surface Area 113
XlogP 5.2 Complexity 462
Heavy Atom Count 29 Rotatable Bond Count 21
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 7
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Pore-forming PNC peptide (PNC)
            Cellular tumor antigen p53 (TP53) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockout of TP53
                      Induced Change 1-Oleoyl-sn-glycerol 3-phosphate concentration: decrease
                      Summary Introduced Variation         Induced Change 
                      Disease Status Colon cancer [ICD-11: 2B90]
                      Details It is reported that knockout of TP53 leads to the decrease of 1-oleoyl-sn-glycerol 3-phosphate levels compared with control group.
References
1 Integrative omics analysis of p53-dependent regulation of metabolism. FEBS Lett. 2018 Feb;592(3):380-393.

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