Details of Metabolite

General Information of MET (ID: META01209)
Name L-beta-Homoproline hydrochloride
Synonyms   Click to Show/Hide Synonyms of This Metabolite
53912-85-9; (S)-2-(Pyrrolidin-2-yl)acetic acid hydrochloride; (S)-2-(Pyrrolidin-2-yl)acetic acid hydrochloride; L-beta-Homoproline HCl; 2-Pyrrolidineacetic acid, hydrochloride, (2S)-; MFCD07363484; (S)-3-(Pyrrol-idinecarboxylic acid hydrochloride; (S)-3-PYRROLIDINECARBOXYLIC ACID HYDROCHLORIDE; L-beta-Homoproline hydrochloride, 98%; (S)-2-(2-Pyrrolidinyl)acetic acid hydrochloride; L-beta-HomoPro.HCl; (R)-2-(2-Pyrrolidinyl)acetic acid hydrochloride
Structure Type Organo heterocyclic compounds
PubChem CID
2761540
Formula
C6H12ClNO2
Structure
<iframe style="width: 300px; height: 300px;" frameborder="0" src="https://embed.molview.org/v1/?mode=balls&cid=2761540"></iframe>
3D MOL is unavailable 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
Physicochemical Properties Molecular Weight 165.62 Topological Polar Surface Area 49.3
XlogP N.A. Complexity 114
Heavy Atom Count 10 Rotatable Bond Count 2
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 3
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Pore-forming PNC peptide (PNC)
            Cellular tumor antigen p53 (TP53) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockout of TP53
                      Induced Change L-beta-Homoproline hydrochloride concentration: decrease
                      Summary Introduced Variation         Induced Change 
                      Disease Status Colon cancer [ICD-11: 2B90]
                      Details It is reported that knockout of TP53 leads to the decrease of L-beta-Homoproline hydrochloride levels compared with control group.
References
1 Integrative omics analysis of p53-dependent regulation of metabolism. FEBS Lett. 2018 Feb;592(3):380-393.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhang and Dr. Mou.