Details of Metabolite

General Information of MET (ID: META01205)
Name Riboprine
Synonyms   Click to Show/Hide Synonyms of This Metabolite
Riboprine; 7724-76-7; N6-(3-Methyl-2-butenyl)adenosine; 2iPA; Isopentenyladenosine; N6-(2-Isopentenyl)adenosine; Isopentenyladenosine riboside; Riboprina; Riboprinum; 6-(gamma,gamma-Dimethylallylamino)purine riboside; 2-IPA; ADENOSINE, N-(3-METHYL-2-BUTENYL)-; N6-Isopentenyladenosine; 6-(3-Methyl-2-butenylamino)purine riboside; UNII-8EU82FAZ5J; Dimethylallyladenosine; N-(3-methylbut-2-en-1-yl)adenosine; N-Isopentenyladenosine; Isopentenyl adenosine; Isopentenyl adenine riboside
Structure Type   Purine ribonucleotides  (Click to Show/Hide the Complete Structure Type Hierarchy)
Nucleosides, nucleotides, and analogues
Purine nucleotides
Purine ribonucleotides
PubChem CID
23982
Formula
C15H21N5O4
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
Physicochemical Properties Molecular Weight 335.36 Topological Polar Surface Area 126
XlogP 1.1 Complexity 461
Heavy Atom Count 24 Rotatable Bond Count 5
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 8
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Pore-forming PNC peptide (PNC)
            Cellular tumor antigen p53 (TP53) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockout of TP53
                      Induced Change Riboprine concentration: increase
                      Summary Introduced Variation         Induced Change 
                      Disease Status Colon cancer [ICD-11: 2B90]
                      Details It is reported that knockout of TP53 leads to the increase of riboprine levels compared with control group.
References
1 Integrative omics analysis of p53-dependent regulation of metabolism. FEBS Lett. 2018 Feb;592(3):380-393.

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