Details of Metabolite

General Information of MET (ID: META01197)
Name Cyclopropanecarboxylic acid
Synonyms   Click to Show/Hide Synonyms of This Metabolite
CYCLOPROPANECARBOXYLIC ACID; 1759-53-1; Carboxycyclopropane; Cyclopropylcarboxylic acid; Cyclopropionic acid; Cyclopropanecarboxylicacid; Cyclopropane carboxylic acid; CPC-acid; MFCD00001287; UNII-008803351S; cyclopropyl carboxylic acid; Cyclopropane-carboxylic acid; NSC1112; 008803351S; Cyclopropanecarboxylic acid, 98%; NSC 1112; EINECS 217-162-5; Trimethylenecarboxylic acid; cyclopropane carboylic acid; BRN 0969839; AI3-30542
Structure Type   Amino acids, peptides, and analogues  (Click to Show/Hide the Complete Structure Type Hierarchy)
Organic acids and derivatives
Carboxylic acids and derivatives
Amino acids, peptides, and analogues
PubChem CID
14985
Formula
C4H6O2
Structure
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3D MOL 2D MOL
  Click to Show/Hide the Molecular/Functional Data (External Links/Property/Function) of This Metabolite
Physicochemical Properties Molecular Weight 86.09 Topological Polar Surface Area 37.3
XlogP 0.6 Complexity 73.6
Heavy Atom Count 6 Rotatable Bond Count 1
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 2
Regulatory Network
Full List of Protein(s) Regulating This Metabolite
      Pore-forming PNC peptide (PNC)
            Cellular tumor antigen p53 (TP53) Click to Show/Hide the Full List of Regulating Pair(s):   1 Pair(s)
               Detailed Information Protein   Info click to show the details of this protein
               Regulating Pair Experim Info click to show the details of experiment for validating this pair [1]
                      Introduced Variation Knockout of TP53
                      Induced Change Cyclopropanecarboxylic acid concentration: decrease
                      Summary Introduced Variation         Induced Change 
                      Disease Status Colon cancer [ICD-11: 2B90]
                      Details It is reported that knockout of TP53 leads to the decrease of cyclopropanecarboxylic acid levels compared with control group.
References
1 Integrative omics analysis of p53-dependent regulation of metabolism. FEBS Lett. 2018 Feb;592(3):380-393.

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